This substance is used in the following areas: printing and recorded media reproduction, health services and scientific research and development. Values are generally displayed in milligram per kilo soil (dry weight). ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. By summarising this information in a single page, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Displayed are the RANGES of min – max of values (provided in %). 2-methylbutanedioic acid is a dicarboxylic acid that is butanedioic acid substituted at position 2 by a methyl group. Active substance approval – indicates if the substance is an approved biocidal active substance. No data available: testing technically not feasible. 1 Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc. Malonic acid and succinic acid each have two different pKa values. It is a conjugate acid of a methylsuccinate. Explain clearly why the first pKa of malonic acid is lower than the first pKa of succinic acid, and why the second pKa of malonic acid is higher than the second pKa of succinic acid. Log Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. Succinic acid is byproduct of sugar fermentation, and is present in wines and beer. If so, the data provided is not processed for the Brief Profile. Our company acquires ISO9001:2000 Quality authentication system and STAR-K authentication. BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material. . This section displays the values related to reproductive toxicity from all registered dossiers for the substance. When more than one result is available per endpoint the ‘worst case’ or most conservative of all the data values provided are displayed, applying a precautionary principal. Thirdly the display of data is prioritised by unit. there is no manual verification or assessment of the correctness of the data. PBT properties are derived from REACH registered substances dossiers. Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)The REACH Regulation (1907/2006) entered into force on 1 June 2007. Succinic acid (CAS No.110-15-6 ) also known as butanedioic acid, asuccin, amber acid, succinicum acidum, katasuccin, bernsteinsaure, dihydrofumaric acid, succinate, kyselina jantarova is a is a common natural organic acids. As a diprotic acid, succinic acid undergoes two successive deprotonation reactions: List of substances subject to the POPs Regulation - Indicates if the substance is included in the POPs Regulation. The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. The physical state and form of a substance can play a significant impact when the hazards of a substance are assessed. minadepiedras.com. This section summarises the values related to aquatic/sediment bioaccumulation in all registered dossiers for the substance. The Agency thus cannot guarantee the correctness of the information displayed. Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre. Thirdly the display of data is prioritised by units. More detailed information is available in the dossiers. Data is generally displayed in milligrams per kilogram sediment (dry weight) or in milligram per litre. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. pH of Succinic Acid. This section summarises the values related to toxicity to soil macroorganisms (except arthropods) from all registered dossiers for the substance. BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. C&L Inventory . EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. The information has not been reviewed or verified by ECHA or any other authority. If so, the data provided is not processed in the Brief Profile. Other names. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. Almost infinite esters can be obtained from carboxylic acids. Data is generally standardised and displayed in milligram per litre/cubic metre. Nulla pulvinar vitae nunc vitae sagittis. Sed elementum odio augue, eget iaculis lorem faucibus vel. If impurities and/or additives have been identified, an informative sentence is displayed below the graphic. Substances may have impurities and additives that lead to different classifications. The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry. While the Agency tries to aggregate the information on chemicals in the best possible way, ECHA cannot check whether all the information provided by industry is free of errors. Due to the number of the substances and the associated information, substance data is processed and aggregated in an automatic process. Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. 110-15-6. 100 mM 10 mM 1 mM. Pre-registration – indicated if the substance is included in the list of pre-registered substances. This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). This site is not fully supported in Internet Explorer 7 (and earlier versions). Currently, succinic acid is primarily produced through chemical processes, such as hydrogenation. Buffer pKa and pH Range Values For preparation of . Data is generally standardised and displayed in in milligram per kilo of food. The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. Koc at 20°C provides substance information on the substance’s Koc adsorption at a temperature 20 °C. Registrants can choose from the following picklist endpoint conclusions: Inhalation route provides substance information on the substance’s acute toxicity via the inhalation route. ... pKa at 20°C provides numerical substance information on the dissociation constant in pKa at a temperature of 20°C. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). This section displays all the public names and other identifiers available in ECHA's databases for the substance. If the substance has no EC number attributed, ECHA will attribute a list number. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance. For accuracy reasons, substance manufacturers and importers are responsible for consulting official sources. When submitted by the lead of a joint submission, the classifications may also reveal agreement between companies. Trade names gives all public trade names submitted to ECHA in REACH registrations. 3 . Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions. Other relevant information includes the following: To see the full list of notified classifications and have more information on impurities and additives relevant to classification, you can consult the C&L Inventory. If more than one result is available per endpoint, the range of results (min-max, RANGE method) will be presented. Also known as: butanedioic acid 100 mM. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. For a detailed overview on identified uses and environmental releases, please consult the detailed information from the registration dossiers. Values are generally displayed in milligram per kilo soil (dry weight). To confirm if a substance is covered by a specific legislative framework the official publication should be consulted.Reproduction or further distribution of this information may be subject to copyright protection. Values provided in ppb and Vol% are provided separately. More information about the EC Inventory can be found here. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Succinic acid, H2C4H4O4, is a weak diprotic acid, pKa1 = 4.21 and pKa2 = 5.64 at 25 degrees celsius.).? Candidate List – indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). This section summarises the flash point values from all registered dossiers for the substance. 3 Long-term EC10 or LC10 or NOEC for mammals provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the mammals in the test, or the no observed effect concentration for mammals. This substance is used for the manufacture of: chemicals, plastic products and textile, leather or fur. Identification Name Succinic acid Accession Number DB00139 Description. Harmonised C&L– indicates if a European Union harmonised classifications and labelling has been assigned to the substance according to Annex VI to CLP and subsequent ATPs. Information in the guidance on safe use section consists of recommendations by a substance registrant(s) on the proper use of the substance in various situations. Release to the environment of this substance can occur from industrial use: formulation of mixtures. This section summarises the surface tension values from all registered dossiers for the substance. This substance is used in the following areas: municipal supply (e.g. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). The quality and correctness of the information remains the responsibility of the data submitter. ChEBI. Values are generally displayed in milligram per kilo food. This section summarises the values related to distribution modelling from all registered dossiers for the substance. Long-term EC10 or LC10 or NOEC for birds provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the birds in the test, or the no observed effect concentration for birds. Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C. See information under ‘Study results oral’. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. As the critical effect is local, succinic acid is assigned to Peak Limitation Category I. The Agency thus cannot guarantee the correctness of the information displayed. The Agency thus cannot guarantee the correctness of the information displayed. Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. O. Since fermentation of succinic acid is considered a CO2 fixing process, this would turn a by-product of the first process into an input for the second [Urbance et al., 2004, McKinlay and Vieille, 2007]. Surface tension provides substance information on the surface tension in (milli)Newton per metre in a concentration in (milli)gram per metre and at a temperature measured in °C. 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Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. For this endpoint registrants do not provide summary data. This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers, the low energy manipulation of substances bound in materials or articles and non-industrial spraying. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals. Note: If the measurement condition (percentage of organic carbon) is not provided by the registrant for adsorption coefficient Kd, the data provided is not processed for the Brief Profile. Thirdly the display of data is prioritised by units. If multiple values are available, the most conservative value (the highest percentage) is displayed. EC10 / LC10 or NOEC for marine water algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water algae or the no observed effect concentration for marine water algae. (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain, MOEHS CATALANA, Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain, PURAC bioquímica, Gran Vial 19-25 08160 Montmeló (Barcelona) Spain, REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland, ROQUETTE ITALIA SPA, Via Serravalle 26 15063 Cassano Spinola Alessandria Italy, SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany, Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom, TRIGON Chemie GmbH, Breitwiesenstr. Precautionary measures and guidance on safe use concern the use and handling of the specific substance, not of the presence of the substance in other articles or mixtures. Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C. LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre. In one of the forms it exists as a salt with sodium. Oxalic Acid – C. 2. Data is generally displayed in milligram per kilo bodyweight. The REACH regulatory processes identified for the Brief Profile are: Persistent Organic Pollutants (POPs)The POPs Regulation (EU) 2019/1021 entered into force on 15 July 2019, repealing the previous POPs Regulation (EC) No 850/2004. PNEC STP, data displayed in milligram per litre. EC10 / LC10 or NOEC for marine water invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water invertebrates or the no observed effect concentration for marine water invertebrates. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile. Oral route provides substance information on the substance’s acute toxicity via the oral route. Authentication system and STAR-K authentication technical development zone, Anhui, Escrow ServiceMoreSecure Orders. Application for Analysis of Sodium succinate on succinic acid pka 100 succinic acid in the EC.. Of 20°C Vol % are provided separately the candidate list of pre-registered substances of... And legally binding information as below, except: ‘ see summary inhalation effects! 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